Semax (ACTH 4-7 Pro8Gly9Pro10)
Cognitive enhancement and neuroprotection
Dosage
200–900 mcg per day
Half-Life
~1–2 minutes (but effects last 20+ hours)
Administration
Nasal spray (most common) or subcutaneous injection
Research Status
Well-Studied
Semax is a synthetic peptide analogue of ACTH (adrenocorticotropic hormone) developed in Russia. It is one of the most potent nootropic peptides available, with strong effects on cognition, focus, and neuroprotection.
Semax increases BDNF and NGF (nerve growth factor) expression, enhances dopamine and serotonin neurotransmission, and has potent neuroprotective effects. It also modulates the HPA axis and has anti-inflammatory effects in the CNS.
This information is for educational purposes only. Always consult a qualified healthcare professional before beginning any peptide protocol.
Dosage
200–900 mcg per day
Half-Life
~1–2 minutes (but effects last 20+ hours)
Administration
Nasal spray (most common) or subcutaneous injection
Medical Disclaimer: The information provided on this page is for educational purposes only and does not constitute medical advice. Peptides may be regulated differently in your jurisdiction. Consult a licensed healthcare provider before use.